Losing weight is hard. Losing weight and then keeping it off is even harder. Case in point: 74% of adults in the United States are overweight or obese, and weight loss is a $20 billion industry. All that said, if you’re trying to slim down, there’s no reason to lose hope. Plenty of studies show that lasting weight loss is not a myth. Work some of the 57 research-backed food, exercise, and lifestyle tips that follow into your routine, and watch the pounds start to come off.